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Some bacterial species (e.g., Acinetobacter ), can provoke nutrient-insensitive states, whereas others, particularly those affecting the GPCR120 receptor, influence lipid-induced GLP-1 production 39

In muscle tissue of aged mice, lowered level of pro-inflammatory markers IL-1, TNF-, and IL-6 was observed after GLP-1RA dulaglutide treatment (Khin et al., 2021

Berberine and saffron stimulate natural GLP-1 production, chromium stabilizes blood sugar, 5-HTP boosts serotonin-driven satiety, and bupleurum maintains gut and liver function

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